Dickkopf-1: As a Diagnostic and Prognostic Serum Marker for Hepatocellular Carcinoma
نویسندگان
چکیده
منابع مشابه
Serum thioredoxin is a diagnostic marker for hepatocellular carcinoma
Here we found that serum levels of thioredoxin were increased in patients with hepatocellular carcinoma (HCC). The optimum diagnostic cutoff for thioredoxin was 20.5 ng/mL (area under curve [AUC] 0.946 [95% CI 0.923-0.969] in the training cohort; 0.941 [0.918-0.963] in the validation cohort). High serum concentrations of thioredoxin differentiated HCC from chronic liver diseases and cirrhosis (...
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We reviewed the tumor markers for hepatocellular carcinoma, with special reference to the roles of Dickkopf-1 and α-fetoprotein in hepatocellular carcinoma.
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conclusions the established method has an acceptable performance in quantifying yb-1. in addition, serum yb-1 may aid in the diagnosis of hcc. results the developed method was linear to 150 μg/l of yb-1 with a minimum detection limit of 0.01 μg/l. the average recoveries were between 93.9% and 109.0%. the mean intra- and inter-assay coefficients of variation (cvs) were 4.0-4.8% and 8.2-10.2%, re...
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BACKGROUND The purpose of this study was to evaluate the potential value of circulating miRNA-122a and miRNA-221 in the diagnosis of hepatocellular carcinoma. METHODS Serum samples were obtained from 85 patients with hepatocellular carcinoma and 85 age-matched and sex-matched healthy volunteers. miRNAs were isolated from the serum samples, and alfa-fetoprotein levels were determined. Expressi...
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ژورنال
عنوان ژورنال: Afro-Egyptian Journal of Infectious and Endemic Diseases
سال: 2016
ISSN: 2090-7184
DOI: 10.21608/aeji.2016.9974